Fetal Megacystic Spontaneus Resolution: A Case Report
Article Main Content
About 1 in 1500 pregnancies have fetal megacystis discovered during the first trimester ultrasound. Because of obstructive or non-obstructive factors, the fetal bladder may appear enlarged. In the first instance, a lower urinary tract obstruction (LUTO) or obstruction of the bladder outlet causes an increase in hydronephrosis, increased renal parenchymal echogenicity, and oligohydramnios beginning in the second trimester. This condition is associated with poor postnatal renal function and high perinatal mortality. Unusual conditions like the megacystis-microcolon-intestinal hypoperistalsis syndrome are uncommon and are among the non-obstructive causes. Megacystis does not always progress as the pregnancy progresses, and earlier research has even documented spontaneous resolution of the condition while pregnant. Prenatal counseling for fetal megacystis is difficult because of the condition's variable etiology, evolution, and prognosis
References
-
Sebire NJ, Von Kaisenberg C, Rubio C, Snijders RJ, Nicolaides KH. Fetal megacystis at 10-14 weeks of gestation. Ultrasound Obstet Gynecol. 1996; 8(6): 387-390.
DOI |
Google Scholar
1
-
McHugo J, Whittle M. Enlarged fetal bladders: aetiology, management and outcome. Prenat Diagn. 2001; 21(11): 958-963.
DOI |
Google Scholar
2
-
Clayton DB, Brock JW 3rd. Lower urinary tract obstruction in the fetus and neonate. Clin Perinatol. 2014; 41(3): 643-659.
DOI |
Google Scholar
3
-
Malin G, Tonks AM, Morris RK, Gardosi J, Kilby MD. Congenital lower urinary tract obstruction: a population-based epidemiological study. BJOG. 2012; 119(12): 1455-1464.
DOI |
Google Scholar
4
-
Tuzovic L, Anyane-Yeboa K, Mills A, Glassberg K, Miller R. Megacystis-microcolon-intestinal hypoperistalsis syndrome: case report and review of prenatal ultrasonographic findings. Fetal Diagn Ther. 2014; 36(1): 74-80.
DOI |
Google Scholar
5
-
Machado L, Matias A, Rodrigues M, Mariz C, Monteiro J, Montenegro N. Fetal megacystis as a prenatal challenge: megacystis-microcolon-intestinal hypoperistalsis syndrome in a male fetus. Ultrasound Obstet Gynecol. 2013; 41(3): 345-347.
DOI |
Google Scholar
6
-
Liao AW, Sebire NJ, Geerts L, Cicero S, Nicolaides KH. Megacystis at 10-14 weeks of gestation: chromosomal defects and outcome according to bladder length. Ultrasound Obstet Gynecol. 2003; 21(4): 338-341.
DOI |
Google Scholar
7
-
Bornes M, Spaggiari E, Schmitz T, Dreux S, Czerkiewicz I, Delezoide AL, et al. Outcome and etiologies of fetal megacystis according to the gestational age at diagnosis. Prenat Diagn. 2013; 33(12): 1162-1166.
DOI |
Google Scholar
8
-
Fievet L, Faure A, Coze S, Harper L, Panait N, Braunstein D, et al. Fetal megacystis: etiologies, management, and outcome according to the trimester. Urology. 2014; 84(1): 185-190.
DOI |
Google Scholar
9
-
Confer SD, Galati V, Frimberger D, Kropp BP. Megacystis with an anterior urethral valve: case report and review of literature. J Pediatr Urol. 2010; 6(5): 459-462.
DOI |
Google Scholar
10
-
Montemarano H, Bulas DI, Rushton HG, Selby D. Bladder distention and pyelectasis in the male fetus: causes, comparisons, and contrasts. J Ultrasound Med. 1998; 17(12): 743-749.
DOI |
Google Scholar
11
-
Müller Brochut AC, Thomann D, Kluwe W, Di Naro E, Kuhn A, Raio L. Fetal megacystis: experience of a single tertiary center in Switzerland over 20 years. Fetal Diagn Ther. 2014; 36(3): 215-222.
DOI |
Google Scholar
12
-
Jouannic JM, Hyett JA, Pandya PP, Gulbis B, Rodeck CH, Jauniaux E. Perinatal outcome in fetuses with megacystis in the first half of pregnancy. Prenat Diagn. 2003; 23(4): 340-344.
DOI |
Google Scholar
13
-
Corteville JE, Gray DL, Crane JP. Congenital hydronephrosis: correlation of fetal ultrasonographic findings with infant outcome. Am J Obstet Gynecol. 1991; 165(2): 384-388.
DOI |
Google Scholar
14
-
Ruano R, Yoshisaki CT, Salustiano EM, Giron AM, Srougi M, Zugaib M. Early fetal cystoscopy for first-trimester severe megacystis. Ultrasound Obstet Gynecol. 2011; 37(6): 696-701.
DOI |
Google Scholar
15
-
Newman J, Antonakopoulos GN. The fine structure of the human fetal urinary bladder. Development and maturation. A light, transmission and scanning electron microscopic study. J Anat. 1989; 166: 135-150.
Google Scholar
16
-
Satoh S, Inatomi S, Kubota M, Suita S, Nakano H. Antenatal sonographic detection of vesicoureteral reflux. A case report. Fetal Diagn Ther. 2002; 17(5): 277-280.
DOI |
Google Scholar
17
-
Stewart GD, Ahluwalia A, Gowland M. Case report: diagnosis of fetal vesicoureteric reflux as the cause of pelvicalyceal dilatation on antenatal ultrasound. Clin Radiol. 1995; 50(3): 192-194.
DOI |
Google Scholar
18
-
Leung VY, Chu WC, Metreweli C. Hydronephrosis index: a better physiological reference in antenatal ultrasound for assessment of fetal hydronephrosis. J Pediatr. 2009; 154(1): 116-120.
DOI |
Google Scholar
19
-
Nijagal A, Sydorak RM, Feldstein VA, Hirose S, Albanese CT. Spontaneous resolution of prenatal megalourethra. J Pediatr Surg. 2004; 39(9): 1421-1423.
DOI |
Google Scholar
20
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