Synovial Sarcoma of the Parotid Gland A Case Report and Review of Literature

Synovial Sarcoma of the Parotid Gland A Case Report and Review of Literature



HTML
25

Total
19

Citations

Share

##plugins.themes.bootstrap3.article.sidebar##

##plugins.themes.bootstrap3.article.main##

The clinicopathologic characteristics of the head and neck Synovial sarcoma are scant. The parotid gland localization of this unusual neoplasm of mesenchymal derivation is most likely to be misdiagnosed as primary mesenchymal, myoepithelial, or metastatic neoplasm.

We report a case of synovial sarcoma in the parotid gland in a young enfant that underwent total resection of the parotid tumor after the failure of the initial chemotherapy. Adding to many studies, to determine the radiologic and histologic features that lend a hand in the proper diagnostic, as well as highlighting the prognostic factors for a favorable outcome.

Keywords: Mesenchymal cells parotid gland primary synovial sarcoma Synovial sarcoma
  1. Luksic M, Virag S, Manojlovic B, Obradovic D, Macan J, Stepan. Primary synovial sarcoma of the parotid gland in 15-year-old boy. Journal of Cranio-Maxillo-Facial Surgery. 2011; 39: 445-448.
    DOI
     Google Scholar 
  2. Barkan GA, El-Naggar AK. Primary Synovial Sarcoma of the Parotid Gland. Annals of Diagnostic Pathology. 2004; 8(4): 233-236.
    DOI
     Google Scholar 
  3. Kartha SS, Bumpous JM. Synovial cell sarcoma: diagnosis, treatment, and outcomes. Laryngoscope. 2002; 112(11): 1979e1982.
    DOI
     Google Scholar 
  4. SHMOOKLER BM, Enzinger FM, Brannon RB. Orofacial Synovial Sarcoma A Clinicopathologic Study of 11 New Cases and Review of The Literature. Cancer. 1982; 50: 269-276.
    DOI
     Google Scholar 
  5. Jay A, Hutchison I, Piper K, Farthing PM, Richards PS. Synovial sarcoma presenting as a parotid mass: case report and review of literature. Head Neck. 2008; 30(12): 1654e1659.
    DOI
     Google Scholar 
  6. Fisher C. Synovial sarcoma. Ann Diagn Pathol. 1998; 2(6): 401e421.
    DOI
     Google Scholar 
  7. Harb WJ, Luna MA, Patel SR, Ballo MT, Roberts DB, Sturgis EM. Survival in patients with synovial sarcoma of the head and neck: association with tumor location, size, and extension. Head Neck. 2007; 29(8): 731e740.
    DOI
     Google Scholar 
  8. Hirsch RJ, Yousem DM, Loevner LA, Montone KT, Chalian AA, Hayden RE, et al. Synovial sarcomas of the head and neck: MR findings. AJR Am J Roentgenol. 1997; 169(4): 1185e1188.
    DOI
     Google Scholar 
  9. Roth JA, Enzinger FM, Tannenbaum M. Syovial sarcoma of the neck: a follow-up study of 24 cases. Cancer. 1975; 35: 1243-1253.
    DOI
     Google Scholar 
  10. Varela-Duran J, Enzinger FM. Calcifying synovial sarcoma. Cancer. 1982; 50: 3.
    DOI
     Google Scholar 
  11. Kikuchi I, Anbo J, Nakamura S, Sugai T, Sasou S, Yamamoto M, et al. Synovial sarcoma of the thyroid. Report of a case with aspiration cytology findings and gene analysis. Acta Cytol. 2003; 47: 495-500.
    DOI
     Google Scholar 
  12. Kilpatrick SE, Teot LA, Stanley MW, Ward WG, Savage PD, Geisinger KR. Fine-Needle Aspiration Biopsy of Synovial Sarcoma: A Cytomorphologic Analysis of Primary, Recurrent, and Metastatic Tumors. Am J Clin Pathol. 1996; 106(6): 769-775.
    DOI
     Google Scholar 
  13. Guillou L, Kraus MD, Dei Tos AP, Fletcher CD. S100 protein reactivity in synovial sarcomas: a potentially frequent diagnostic pitfall. Immunohistochemical analysis of 100 cases. Appl Immunohistochem. 1996; 4: 167-175.
     Google Scholar 
  14. Smith TA, Machen SK, Fisher C, Goldblum JR. Usefulness of cytokeratin subsets for distinguishing monophasic synovial sarcoma from malignant peripheral nerve sheath tumour. Am J Clin Pathol. 1999; 112: 641-648.
    DOI
     Google Scholar 
  15. Crew AJ, Clark J, Fisher C, Gill S, Grimer R, Chand A, et al. Fusion of SYT to two genes, SSX1 and SSX2 encoding proteins with homology to the Kruppel associated box in human synovial sarcoma. EMBO J. 1995; 10: 2333-2340.
    DOI
     Google Scholar 
  16. Fisher C, De Bruijn DRH, Geurts van Kessel A. Synovial sarcoma. In: Fletcher CDM, Unni KK, Mertens F, editors. World Health Organization classification of tumours. Pathology and genetics of soft tissue and bone. Lyon: IARC; 2002: 200-204.
     Google Scholar 
  17. Ellis GL, Auclair PL. Atlas of tumor pathology. In: Third Series Fascicle 17. Tumors of the salivary glands. Washington, DC: Armed Forces Institute of Pathology. 1996: 375e385.
     Google Scholar 
  18. Rigante M, Visocchi M, Petrone G, Mulè A, Bussu F. Synovial sarcoma of the parotid gland: a case report and review of the literature. ACTA Otorhinolaryngologica Italica. 2011; 31: 43-46.
     Google Scholar 
  19. Bergh P, Meis-Kindblom JM, Gherlinzoni F, Berlin O, Bacchini P, Bertoni F, et al. Synovial sarcoma: identification of low and high risk groups. Cancer. 1999; 85(12): 2596e2607.
    DOI
     Google Scholar 
  20. Dei Tos AP, Dal Cin P, Sciot R, Furlanetto A, Da Mosto MC, Giannini C, et al. Ferlito A: synovial sarcoma of the larynx and hypopharynx. Ann Otol Rhinol Laryngol. 1998; 107(12): 1080e1085.
    DOI
     Google Scholar 
  21. Bukachevsky RP, Pincus RL, Shechtman FG, Sarti E, Chodosh P. Synovial sarcoma of the head and neck. Head & Neck. 1992; 14(1): 44-48.
    DOI
     Google Scholar 
  22. Olsen RJ, Lydiatt WM, Koepsell SA, Lydiatt D, Johansson SL, Naumann S, et al. C‐erb‐B2 (HER2/neu) expression in synovial sarcoma of the head and neck. Head & Neck: Journal for the Sciences and Specialties of the Head and Neck. 2005; 27(10): 883-892.
    DOI
     Google Scholar 
  23. Spillane AJ, A’Hern R, Judson IR, Fisher Meirion Thomas CJ. Synovial Sarcoma: A Clinicopathologic, Staging, and Prognostic Assessment. ournal of Clinical Oncology. 2000; 18(22): 3794-3803.
    DOI
     Google Scholar 
  24. Amble FR, Olsen KD, Nascimento AG, Foote RL. Head and neck synovial cell sarcoma. Otolaryngol Head Neck Surg. 1992; 107(5): 631e637.
    DOI
     Google Scholar 
  25. Tilakaratne WM. Synovial sarcoma of the mandible. J Oral Pathol Med. 2006; 35(1): 61e63.
    DOI
     Google Scholar 
  26. Ferrari A, Casanova M, Massimino M, Luksch R, Cefalo G, Lombardi F, et al. Synovial sarcoma: report of a series of 25 consecutive children from a single institution. Med Pediatr Oncol. 1999; 32(1): 32e37.
    DOI
     Google Scholar 
  27. Thompson Jr RC, Garg A, Goswitz J, Cheng EY, Clohisy DR, Dusenbery K. Synovial sarcoma. Large size predicts poor outcome. Clin Orthop Relat Res. 2000; 373: 18e24.
    DOI
     Google Scholar 
  28. Barnes L. Tumors and tumor-like lesions of the soft tissues. In: Barnes L (ed.), Surgical pathology of the head and neck. Revised and expanded (in three volumes), vol. 2. New York, Basel: Marcel Dekker, Inc., 2001: 889e1048.
     Google Scholar 
  29. Kouhen F, Afif M, Benhmidou N, Rais F, Khmou M, Cherradi N, et al. Le synovialosarcome de la sphère oto-rhino-laryngée: une localisation rare: à propos de deux cas. The Pan African Medical Journal. 2015; 20. French.
    DOI
     Google Scholar 

How to Cite

Rochdi, Y., Rizkou, F., Oulghoul, O., Benhoummad, O., & Raji, A. (2023). Synovial Sarcoma of the Parotid Gland A Case Report and Review of Literature. European Journal of Medical and Health Sciences, 5(2), 10–13. https://doi.org/10.24018/ejmed.2023.5.2.1538

Search Panel

Youssef Rochdi
Google Scholar
Pubmed
Ejmed Journal

FatimaEzzahra Rizkou
Google Scholar
Pubmed
Ejmed Journal

Omar Oulghoul
Google Scholar
Pubmed
Ejmed Journal

Othmane Benhoummad
Google Scholar
Pubmed
Ejmed Journal

Abdelaziz Raji
Google Scholar
Pubmed
Ejmed Journal

Most read articles by the same author(s)