Nasopharngeal Tuberculosis Simulating Cancer:  About 2 Cases

F. Hadid; O. Oulghoul; H. Benjelloun; O. Benhommad; A. Raji; Y. Rochdi

doi:10.24018/ejmed.2021.3.3.852

Case Study

F. Hadid

Mohammed VI University Hospital, Morocco

* Corresponding author

O. Oulghoul

Mohammed VI University Hospital, Morocco

H. Benjelloun

Mohammed VI University Hospital, Morocco

O. Benhommad

Mohammed VI University Hospital, Morocco

A. Raji

Mohammed VI University Hospital, Morocco

Y. Rochdi

Mohammed VI University Hospital, Morocco

10.24018/ejmed.2021.3.3.852

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Submitted 2021-05-02
Published 2021-05-28

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Abstract

Primitive tuberculosis of the nasopharynx is rare. Clinical symptoms and paraclinical examinations are often confusing. Pseudotumour forms are frequent, which poses a problem of differential diagnosis with cavum cancer. We reported two cases of nasopharyngeal tuberculosis, followed up in the ear, nose and throat department of the Arrazi Hospital of the Mohammed VI University Hospital in Marrakesh. The first case concerned a 22-year-old female patient admitted to hospital for an etiological assessment of a right spinal adenopathy evolving in a context of altered general condition with weight loss, anorexia, and night sweats. The second case was a 14-year-old patient with a fistulised right spinal adenopathy with nasal obstruction and homolateral deafness. Nasofibroscopy in both patients showed a burgeoning tumour on the right posterolateral wall. A biopsy of the cavum was indicated. The histological study of the biopsies revealed an epithelial-giganto-cellular granuloma with caseous necrosis. This allowed to make the diagnosis of nasopharyngeal tuberculosis, and an antibacillary treatment was instituted. The evolution was favorable.

Keywords: Tuberculosis, nasopharyngeal, nasofibrosopy, histology.

References

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Google Scholar

Nieves CS, Onofre RDC, Aberin-Roldon FCA, Gutierrez RLC. Nasopharyngeal tubeculosis in a patient presenting with upper airway obstruction. Philipp J Otolaryngol Head Neck Surg 2010; 25(1): 20-22.
Google Scholar

Ziad, T., Nouri, H., Adny, A., Rochdi, Y., Aderdour, L., & Raji, A. (2013). Miliaire tuberculeuse aiguë du pharynx ou maladie d’Isambert: à propos d’un cas. Archives de Pédiatrie, 20(1), 41–43.
Google Scholar

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Google Scholar

Noël GE. La tuberculose et les infections à mycobactéries. De la microbiologie à la clinique. La Lettre de l’Infectiologue 1990; V: 716-9.
Google Scholar

Clément P, Leguyadec T, Zalagh M, Gauthier J, N'Zouba L, Kossowski M. Manifestations bucco-naso-sinusiennes des maladies infectieuses spécifiques. EMC ORL. 2005(2): 198-217. PubMed | Google Scholar.
Google Scholar

Tse GM, Ma TK, Chan AB et al. Tuberculosis of the nasopharynx: a rare entity revisited. Laryngoscope. 2003 Apr;113(4):737-40. PubMed | Google Scholar.
Google Scholar

C.Adnane,T.Adouly,T.Oubahmane,S.Rouadi,R.Abada,M.Mahtar,M.Roubal. la tuberculose nasopharyngée à propos de 3 cas. Service d’ORL et chirurgie cervicofacial, Casablanca, Maroc. https://doi.org/10.1016/j.aforl.2014.07.278.
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Google Scholar

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Google Scholar

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Google Scholar

King Ann D, Ahuja Anil T, Tse Gary MK, Van Harselt Adrew CA, Chan Amy BW. MR imaging features of nasopharyngeal tuberculosis: repport of three cases and littérature review. AmJ NeuroRadiol. 2009; 24: 279-282. PubMed | Google Scholar.
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Nasopharngeal Tuberculosis Simulating Cancer: About 2 Cases. (2021). European Journal of Medical and Health Sciences, 3(3), 46-48. https://doi.org/10.24018/ejmed.2021.3.3.852

Issue

Vol. 3 No. 3 (2021)

[1] QUI. Rapport mondial sur la tuberculose. 2014. (Rapport de l'OMS).
Google Scholar

[2] Nieves CS, Onofre RDC, Aberin-Roldon FCA, Gutierrez RLC. Nasopharyngeal tubeculosis in a patient presenting with upper airway obstruction. Philipp J Otolaryngol Head Neck Surg 2010; 25(1): 20-22.
Google Scholar

[3] Ziad, T., Nouri, H., Adny, A., Rochdi, Y., Aderdour, L., & Raji, A. (2013). Miliaire tuberculeuse aiguë du pharynx ou maladie d’Isambert: à propos d’un cas. Archives de Pédiatrie, 20(1), 41–43.
Google Scholar

[4] Bouaity B et coll. Tuberculose du naso-pharynx: à propos d'un cas. Lettre d’ORL et de chirurgie cervico-faciale. 2009; 319 :14-16. PubMed | Google Scholar.
Google Scholar

[5] Noël GE. La tuberculose et les infections à mycobactéries. De la microbiologie à la clinique. La Lettre de l’Infectiologue 1990; V: 716-9.
Google Scholar

[6] Clément P, Leguyadec T, Zalagh M, Gauthier J, N'Zouba L, Kossowski M. Manifestations bucco-naso-sinusiennes des maladies infectieuses spécifiques. EMC ORL. 2005(2): 198-217. PubMed | Google Scholar.
Google Scholar

[7] Tse GM, Ma TK, Chan AB et al. Tuberculosis of the nasopharynx: a rare entity revisited. Laryngoscope. 2003 Apr;113(4):737-40. PubMed | Google Scholar.
Google Scholar

[8] C.Adnane,T.Adouly,T.Oubahmane,S.Rouadi,R.Abada,M.Mahtar,M.Roubal. la tuberculose nasopharyngée à propos de 3 cas. Service d’ORL et chirurgie cervicofacial, Casablanca, Maroc. https://doi.org/10.1016/j.aforl.2014.07.278.
Google Scholar

[9] Kharoubi S. Miliaire tuberculeuse aigue du pharynx: à propos d?une observation. Rev pneumol Clin. 2004; 60(5):296-298. PubMed | Google Scholar.
Google Scholar

[10] Raji A, Essaadi M, Ait Benhamou C, Kadiri F, Laraqui NZ, Benchakroun Y. Aspect rare de la pathologie rhinopharyngée: la tuberculose cavaire. Rev JF ORL 1995; 44: 264-7.
Google Scholar

[11] Zanaret M, Dessi P. Tuberculose pharyngée. EMC ORL 1990;20-575 A10, 2p.
Google Scholar

[12] Marrakchi R, Fathallah M, Ben Ramdane K, Ben Abid H, Sioud H. La tuberculose du cavum, à propos de 2 cas. Rev Laryngol, 1990; 111: 149-52.
Google Scholar

[13] King Ann D, Ahuja Anil T, Tse Gary MK, Van Harselt Adrew CA, Chan Amy BW. MR imaging features of nasopharyngeal tuberculosis: repport of three cases and littérature review. AmJ NeuroRadiol. 2009; 24: 279-282. PubMed | Google Scholar.
Google Scholar

[14] I. Brahami, N. Mehtari, F. Mlata, E. Boukli, F. Mébarki, F. Hadj allal, Les complications chirurgicales du cancer de la thyroïde: a propos de 66 cas, Vol. 131, Issue 4, Supplement, October 2014, Page A124. https://doi.org/10.1016/j.aforl.2014.07.261.
Google Scholar

Nasopharngeal Tuberculosis Simulating Cancer: About 2 Cases

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