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SARS-CoV-2 virus is the major cause of viral disease, COVID-19 which is highly infectious, WHO did its roll out for coordination, policy and technical guidance. About 64.5% of the population globally have had one dose of COVID-19 vaccine. Close to vaccines have been administered with 18.3 million daily. In low middle Countries, approximately 14.5% have received atleast a single dose. A number of researches have come up with vaccines to curb COVID-19 disease. A researches conducted among the exposed people -60 years and above, who are frontline workers, health care workers, persons with comorbidities. Different researches have been carried out in different cities like Quantitative data presented descriptively and qualitative, thematically. A number of factors dictated the willingness to take up the vaccine, these included confidence in the vaccine, more than personal factors of participants. The respondents revealed mistrust from most people both in developed and non-developed countries, believe in God’s protection and ignorance in vaccine development. On the other hand, peer pressure and effectiveness of the vaccination programmes among childhood diseases contributed to low uptake of the vaccine.

Conclusion: attention ought to be given to factors promoting vaccine uptake and misconceptions should be expelled concerning the disease.

Recommendations: Strengthen disease surveillance at all stages and regularly updating of COVID-19 data to national level by vaccinating counties, Counties are required to increase researches on more about the disease, use COVID-19 data for decision making in terms of curbing the disease and give refresher course on health care workers surveillance.

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