Macular Complications of Behcet Disease: What to Expect?



Abstract Views
235

Downloads
190

Citations

Share

##plugins.themes.bootstrap3.article.sidebar##

Submitted Sep 11, 2022
Published Nov 10, 2022
10.24018/ejmed.2022.4.6.1513

Abstract viewed = 235 times

Table of Contents

##plugins.themes.bootstrap3.article.main##

Purpose: To determine the rate of incidence and the most common type of macular complications in patients with Behcet disease.

Methods: In this monocentric retrospective clinical study we examined all patients diagnosed with Behcet disease between April 2018 and April 2022 (150 patients). Each individual would undergo a complete ophthalmological examination, a fundus retinography, OCT scan and fluorescein angiography.

Results: 54 patients out of 150 presented a macular complication (36%). The macular involvement was bilateral in 49 patients. 60% of patients presented with an initial best corrected visual acuity (BCVA) of equal or less than 1/10. The most common types of maculopathy found in our study were cystoid macular edema (60.4% of patients), macular degeneration (32%), macular hole (5.3%) and serous retinal detachment/epimacular membrane (2.3%).

Conclusion: Macular involvement is very common in Behcet syndrome evolution and is responsible for severe and, most often, irreversible sight loss. Therefore, proper and early management of the disease is mandatory in order to minimize visual impairment.

Keywords: Behcet disease, macular complocations, macular edema, ophthalmology

Downloads

Download data is not yet available.

References

  1. Yazici H, Tüzün Y, Pazarli H, Yurdakul S, Ozyazgan Y, Ozdoğan H, et al. Influence of age of onset and patient's sex on the prevalence and severity of manifestations of Behcet's syndrome. Annals of the Rheumatic Diseases. 1984; 43(6): 783-9.
     Google Scholar
  2. Behçet H. Über rezidivierende Aphthose, durch ein Virus verursachte Geshwüre am Munde, am Auge und an den Genitalien. Dermatol Wochenschr. 1937; 105: 1152-1157. German.
     Google Scholar
  3. Ustün C. A famous Turkish dermatologist, Dr. Hulusi Behçet. Eur J Dertmatol. 2002; 12(5): 469-70.
     Google Scholar
  4. Silman AJ. Criteria for diagnosis of Behçet's disease. Lancet. 1990; 335: 1078.
    DOI  |   Google Scholar
  5. Nussenblatt RB. Uveitis in Behçet’s disease. International Reviews of Immunology. 1997; 14: 67-79.
    DOI  |   Google Scholar
  6. Kaçmaz RO, Kempen JH, Newcomb C, Gangaputra S, Daniel E, Levy-Clarke GA, et al. Ocular inflammation in Behçet disease: incidence of ocular complications and of loss of visual acuity. American Journal of Ophthalmology. 2008; 146(6): 828-36.
    DOI  |   Google Scholar
  7. Basic and clinical science course (BCSC), Section 9: Intraocular Inflammation and Uveitis, San Francisco: American Academy of Ophthalmology, 2014.
     Google Scholar
  8. Yazici H, Tüzün Y, Pazarli H, Yurdakul S, Ozyazgan Y, Ozdoğan H, et al. Influence of age of onset and patient's sex on the prevalence and severity of manifestations of Behcet's syndrome. Annals of the Rheumatic Diseases. 1984; 43(6): 783-9.
    DOI  |   Google Scholar
  9. Atmaca LS. Fundus changes associated with Behçet's disease. Graefe's Archive for Clinical and Experimental Ophthalmology. 1989; 227: 340-4.
    DOI  |   Google Scholar
  10. Ouazzani B, Benchekroun N, El Aouni A, Hajji Z, Chaoui Z, Berraho Hamani A. Devenir de la maladie de Behçet en milieu ophtalmologique marocain. Journal Français d'Ophtalmologie. 1995; 18: 373-5. French.
     Google Scholar
  11. Benchekroun O, Lahbil D, Lamari H, Rachid R, El Belhadji M, Laouissi N, et al. La maculopathie dans la maladie de behcet. Journal Français d'Ophtalmologie. 2004; 27(2): 154-159
    DOI  |   Google Scholar
  12. Maalej A, Gabsi S, Rannen R, Ben Achour B, Turki W. Maculopathie au cours de la maladie de behcet. Communication affichée. Société Française d’Ophtalmologie. 2010. French.
     Google Scholar
  13. Gass JD, Norton EW. Follow-up study of cystoid macular edema following cataract extraction. Transactions - Section on Otolaryngology. 1969; 73: 665-682.
     Google Scholar
  14. Hajji Z, Berraho A. Oeil et maladie de behçet; Encycl Méd Chir, Paris. Ophtalmologie. 21-225-C-20. French.
     Google Scholar
  15. Khairallah M, Attia S, Ben Yahia S, Jenzeri S, Ghrissi R, Jelliti B, et al. Pattern of uveitis in Behçet's disease in a referral center in Tunisia, North Africa. International Ophthalmology. 2009; 29: 135-141.
    DOI  |   Google Scholar
  16. Tugal-Tutkun I, Onal S, Altan-Yaycioglu R, Huseyin Altunbas H, Urgancioglu M. Uveitis in Behçet disease: an analysis of 880 patients. American Journal of Ophthalmology. 2004; 138: 373-380.
    DOI  |   Google Scholar
  17. Sheu SJ, Yang CA. Macular hole in Behcet's disease. Kaohsiung Journal of Medical Sciences. 2004; 20: 558-562.
    DOI  |   Google Scholar
  18. Kahloun R, Ben Yahia S, Mbarek S, Attia S, Zaouali S, Khairallah M. Macular involvement in patients with Behçet's uveitis. Journal of Ophthalmic Inflammation and Infection. 2012; 2(3): 121-4.
    DOI  |   Google Scholar


Most read articles by the same author(s)

1 2 > >>