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Background: Acceptance of a COVID-19 vaccine is crucial to achieve sufficient immunization coverage to end the pandemic. After initially focusing on adults, the emphasis of vaccination is now being geared towards the younger generation. In order to mandate vaccines in schools and attain widespread vaccine uptake, it is important to understand the key determinants that influence students’ willingness to receive a COVID-19 vaccine. Hence, this study was designed to explore students’ willingness to receive a vaccine, their concerns regarding vaccination, and additional factors influencing COVID-19 vaccine acceptance.

Method: Descriptive analytic cross-sectional study using snowball and convenience sample technique was conducted from July - September 2021. Social media networks such as Twitter, WhatsApp and Instagram were used. Data from the student population of both genders receiving secondary and post-secondary education was collected from the Asia-Pacific, Middle East, Europe, and America (26-countries from all over the world). Descriptive statistics and Chi square tests were used. Multivariate logistic regression analysis was used to determine significant predictors for vaccine acceptance.

Results: A total of 201 participants completed the questionnaire (response rate 53%). We found considerably higher willingness (85%) to take a COVID-19 vaccine in the sample; highest among students in the West (95.0%), followed by Asia-Pacific region (84.0%) and the least among Middle East (80.0%). A statistically significant association (p = 0.000) was found between the female gender and the willingness for vaccine receival. Preserving health [OR 18.82, 95%CI 2.88-122.80], understanding the importance of vaccinations for protection against COVID 19 [OR 34.28, 95%CI 3.72-315.95], concerns about vaccine safety [OR 1.77, 95%CI1.21-28.78] and worry about potential side effects [OR 0.027, 95%CI 0.004-0.213] were significant predictors for vaccine acceptance.

Conclusion: The majority of students were willing to get the COVID-19 vaccine to protect their health; but there were concerns about safety and side effects. Greater understanding about the importance of the vaccine, for protection against COVID-19 was predictive of willingness to receive the vaccine. This study provided evidence for health authorities to provide clear information, reduce misinformation and design measures to address the fears and worries about the effects of the vaccine. Future qualitative studies should be directed towards understanding differences in students’ perspectives in depth.

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References

  1. WHO Coronavirus (COVID-19) Dashboard. [Internet] [cited on 2022 January 29] Available from: https://covid19.who.int/.
     Google Scholar
  2. Calina D, Docea AO, Egorov AM, Ishmukhametov AA, Gabibov AG, Shtilman MI, et al. Towards effective COVID-19 vaccines: updates, perspectives and challenges. Int J Mol Med. 2020; 46: 3–16.
    DOI  |   Google Scholar
  3. Fazel M, Puntis S, White SR, Townsend A, Mansfield KL, Viner R, et al. Willingness of children and adolescents to have a COVID-19 vaccination: Results of a large whole schools’ survey in England. E Clinical Medicine. 2021; 40: 101144.
    DOI  |   Google Scholar
  4. El-Elimat T, AbuAlSamen MM, Almomani BA, Al-Sawalha NA, Alali FQ. Acceptance and attitudes toward COVID-19 vaccines: A cross-sectional study from Jordan. PLoS ONE. 2021; 16(4): e0250555.
    DOI  |   Google Scholar
  5. World Health Organization. Vaccination: European Commission and World Health Organization join forces to promote the benefits of vaccines. [Internet] 2021 [cited on 2021 Feb 1]. Available from: https://www.who.int/news/item/12-09-2019-vaccination-european-commission-and-world-health-organization-join-forces-to-promote-the-benefits-of-vaccines
     Google Scholar
  6. Peretti-Watel P, Larson HJ, Ward JK, Schulz WS, Verger P. Vaccine hesitancy: clarifying a theoretical framework for an ambiguous notion. PLoS Curr. 2015; 25: 7.
    DOI  |   Google Scholar
  7. Mant M, Aslemand A, Prine A, Jaagumägi Holland A. University students’ perspectives, planned uptake, and hesitancy regarding the COVID-19 vaccine: A multi-methods study. PLoS ONE. 2021; 16(8): e0255447.
    DOI  |   Google Scholar
  8. Al-Mohaithef M, Padhi BK. Determinants of COVID-19 Vaccine Acceptance in Saudi Arabia: A Web-Based National Survey. J Multidiscip Healthc. 2020; 13: 1657–63.
    DOI  |   Google Scholar
  9. Wilson K, Nguyen HH, Brehaut H. Acceptance of a pandemic influenza vaccine: a systematic review of surveys of the general public. Infect Drug Resist. 2011; 4: 197.
    DOI  |   Google Scholar
  10. Kalam MA, Davis TP Jr, Shano S, Uddin MN, Islam MA, Kanwagi R, et al. Exploring the behavioral determinants of COVID-19 vaccine acceptance among an urban population in Bangladesh: Implications for behavior change interventions. PLoS ONE. 2021; 16(8): e0256496.
    DOI  |   Google Scholar
  11. Fadda M, Suggs LS, Albanese E. Willingness to vaccinate against Covid-19: A qualitative study involving older adults from Southern Switzerland. Vaccine X. 2021; 8: 100108.
    DOI  |   Google Scholar
  12. Lazarus J V., Ratzan SC, Palayew A, Gostin LO, Larson HJ, Rabin K, et al. A global survey of potential acceptance of a COVID-19 vaccine. Nat Med. 2020: 1–4.
    DOI  |   Google Scholar
  13. Poehling KA, Blocker J, Ip EH, Peters TR, Wolfson M. 2009–2010 seasonal influenza vaccination coverage among college students from 8 universities in North Carolina. J Am Coll Health. 2012; 60: 541–547.
    DOI  |   Google Scholar
  14. Ryan KA, Filipp SL, Gurka MJ, Zirulnik A, Thompson L. Understanding influenza vaccine perspectives and hesitancy in university students to promote increased vaccine uptake. Helivon. 2019; 5: e02604.
    DOI  |   Google Scholar
  15. Bednarczyk RA, Chu SL, Sickler H, Shaw J, Nadeau JA, McNutt L-A. Low uptake of influenza vaccine among university students: Evaluating predictors beyond cost and safety concerns. Vaccine. 2015; 33: 1659–1663.
    DOI  |   Google Scholar
  16. Sandler K, Srivastava T, Fawole OA, Fasano C, Feemster KA. Understanding vaccine knowledge, attitudes, and decision-making through college student interviews. J Am Coll Health. 2018; 68: 593–602.
    DOI  |   Google Scholar
  17. Larson HJ, Jarrett C, Eckersberger E, Smith DM, Paterson P. Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: a systematic review of published literature, 2007-2012. Vaccine. 2014; 32(19): 2150-9.
    DOI  |   Google Scholar
  18. Solís Arce JS, Warren SS, Meriggi NF, Scacco A, McMurry N, Voors M, Syunyaev G, Malik AA, et al. COVID-19 vaccine acceptance and hesitancy in low- and middle-income countries. Nature Medicine. 2021: 1385-1394.
    DOI  |   Google Scholar
  19. Setbon M, Raude J. Factors in vaccination intention against the pandemic influenza A/H1N1. European Journal of Public Health. 2010; 20(5): 490–494.
    DOI  |   Google Scholar
  20. Betsch C, Wicker S. E-health use, vaccination knowledge and perception of own risk: drivers of vaccination uptake in medical students. Vaccine. 2012; 130(6): 1143-1148.
    DOI  |   Google Scholar
  21. Barello S, Nania T, Dellafiore F, Graffigna G, Caruso R. ‘Vaccine hesitancy’ among university students in Italy during the COVID-19 pandemic. Eur J Epidemiol. 2020; 35: 781–783.
    DOI  |   Google Scholar
  22. Wang J, Jing R, Lai X, Zhang H, Lyu Y, Knoll MD, et al. Acceptance of covid-19 vaccination during the covid-19 pandemic in china. Vaccines. 2020; 8(3): 1–14.
    DOI  |   Google Scholar
  23. Sallam M. COVID-19 Vaccine Hesitancy Worldwide: A Concise Systematic Review of Vaccine Acceptance Rates. Vaccines (Basel). 2021; 9(2): 160.
    DOI  |   Google Scholar
  24. Sallam M, Dababseh D, Eid H, Al-Mahzoum K, Al-Haidar A, Taim D, et al. High rates of COVID-19 vaccine hesitancy and its association with conspiracy beliefs: a study in Jordan and Kuwait among other Arab countries. Vaccines. 2021; 9(1): 42.
    DOI  |   Google Scholar
  25. Lazarus JV, Wyka K, Rauh L, Rabin K, Ratzan S, Gostin LO, et al. Hesitant or Not? The Association of Age, Gender, and Education with Potential Acceptance of a COVID-19 Vaccine: A Country-level Analysis, Journal of Health Communication. 2021; 25: 10: 799-807.
    DOI  |   Google Scholar
  26. Ishimaru T, Okawara M, Ando H, Hino A, Nagata T, Tateishi S, et al. Gender differences in the determinants of willingness to get the COVID-19 vaccine among the working-age population in Japan. Human Vaccines & Immuno Therapeutics. 2021.
    DOI  |   Google Scholar
  27. Saied SM, Saied EM, Kabbash IA, Abdo SA. Vaccine hesitancy: beliefs and barriers associated with COVID-19 vaccination among Egyptian medical students. J Med Virol. 2021; 93: 4280-91.
    DOI  |   Google Scholar
  28. Shen SC, Dubey V. Addressing vaccine hesitancy: Clinical guidance for primary care physicians working with parents. Can Fam Physician. 2019; 65(3): 175-181.
     Google Scholar
  29. Paterson P, Meurice F, Stanberry LR, Glismann S, Rosenthal SL, Larson HJ. Vaccine hesitancy and healthcare providers. Vaccine. 2016; 34(52): 6700–6.
    DOI  |   Google Scholar
  30. Lennon RP, Small ML, Smith RA, Van Scoy LJ, Myrick JG, Martin MA, Group DAR. Unique Predictors of Intended Uptake of a COVID-19 Vaccine in Adults Living in a Rural College Town in the United States. Am J Health Promot. 2022; 36(1): 180-184.
    DOI  |   Google Scholar