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The unprecedented consequences brought by the COVID pandemic are still going on, the virus hasn’t been tamed yet. It is evolving through mutations to consistently being a risk to public health. Recently, the Delta variant has been declared as the variant of concern by the World Health Organization (WHO). In this article, a subvariant of Delta known as Delta Plus has been presented to provide a relevant foundation for future research works. The evolution, pathogenesis, associated symptoms, suggested prevention and treatments, vaccine efficacy, and current trends of transmission of Delta Plus variant of SARS-CoV-2 are reviewed and discussed.

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References

  1. Chowdhury S, Bappy MH, Chowdhury S, Chowdhury MS, Chowdhury NS. Current Review of Delta Variant of SARS-CoV-2. European Journal of Medical and Health Sciences. 2021; 3(6): 23-9.
    DOI  |   Google Scholar
  2. Tracking SARS-CoV-2 variants [Internet]. [cited 2021 Dec 2]. Available from: https://www.who.int/en/activities/tracking-SARS-CoV-2-variants/
     Google Scholar
  3. GISAID - hCov19 Variants [Internet]. [cited 2021 Dec 2]. Available from: https://www.gisaid.org/hcov19-variants/
     Google Scholar
  4. CDC. What you need to know about variants [Internet]. 2021 [cited 2021 Dec 2]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/variants/variant.html
     Google Scholar
  5. Roy B, Roy H. The Delta Plus variant of COVID-19: Will it be the worst nightmare in the SARS-CoV-2 pandemic? Journal of Biomedical Sciences. 2021; 8(1).
    DOI  |   Google Scholar
  6. Kyriakidis NC, López-Cortés A, González EV, Grimaldos AB, Prado EO. SARS-CoV-2 vaccines strategies: a comprehensive review of phase 3 candidates. NPJ Vaccines. 2021; 6(1).
    DOI  |   Google Scholar
  7. Public Health England. SARS-CoV-2 variants of concern and variants under investigation in England. technical briefing 12. 2021.
     Google Scholar
  8. Alexander A. A potentially faster-spreading Delta variant, AY.4.2, has been spotted in 8 states [Internet]. CBS News. 2021 [cited 2021 Dec 2]. Available from: https://www.cbsnews.com/news/covid-delta-plus-variant-ay-4-2-states/
     Google Scholar
  9. Wikipedia contributors. SARS-CoV-2 Delta variant [Internet]. Wikipedia, The Free Encyclopedia. 2021 [cited 2021 Dec 2]. Available from: https://en.wikipedia.org/w/index.php?title=SARS-CoV-2_Delta_variant&oldid=1058079794
     Google Scholar
  10. Becerra A, Muñoz-Velasco I, Aguilar-Cámara A, Cottom-Salas W, Cruz-González A, Vázquez-Salazar A, et al. Two Short Low Complexity Regions (LCRs) are Hallmark Sequences of the Delta SARS-CoV-2 Variant Spike Protein. 2021.
    DOI  |   Google Scholar
  11. Kannan SR, Spratt AN, Cohen AR, Naqvi SH, Chand HS, Quinn TP, et al. Evolutionary analysis of the delta and Delta Plus variants of the SARS-CoV-2 viruses. Journal of Autoimmunity. 2021; 102715.
    DOI  |   Google Scholar
  12. CDC. COVID Data Tracker. [Internet]. 2020 [cited 2021 Dec 2]. Available from: https://covid.cdc.gov/covid-data-tracker/
     Google Scholar
  13. CDC. Delta variant: What we know about the science. [Internet]. 2021 [cited 2021 Dec 2]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/variants/delta-variant.html
     Google Scholar
  14. Burn-Murdoch J. New Delta descendant may be more infectious than its ancestor. Financial Times [Internet]. 2021 [cited 2021 Dec 2]; Available from: https://www.ft.com/content/f1ec9d5d-9e02-4cc4-95e7-1dcbb1844d43
     Google Scholar
  15. Chowdhury S, Bappy MH, Chowdhury S, Chowdhury MS, Chowdhury NS. COVID-19 induced cardiovascular complications and recent therapeutic advances. European Journal of Medical and Health Sciences. 2021; 3(6): 17-22.
    DOI  |   Google Scholar
  16. Ong SWX, Chiew CJ, Ang LW, Mak TM, Cui L, Toh MPH, et al. Clinical and Virological Features of SARS-CoV-2 Variants of Concern: A Retrospective Cohort Study Comparing B. Clinical Infectious Disease. 2021; 1: 1.
     Google Scholar
  17. Fisman D, Tuite A. Progressive Increase in Virulence of Novel SARS-CoV-2 Variants in Ontario. Canada; 2021.
    DOI  |   Google Scholar
  18. CDC. Symptoms of COVID-19. [Internet]. 2021 [cited 2021 Dec 2]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/symptoms-testing/symptoms.html
     Google Scholar
  19. Miller K. What is the Delta Plus variant? Here’s what experts know about it so far. [Internet]. 2021 [cited 2021 Dec 2]. Available from: https://www.prevention.com/health/a37221697/what-is-delta-plus-variant-covid-19/
     Google Scholar
  20. Treatments for COVID-19. [Internet]. 2021 [cited 2021 Dec 2]. Available from: https://www.health.harvard.edu/diseases-and-conditions/treatments-for-covid-19
     Google Scholar
  21. Information on COVID-19 treatment, prevention and research. [Internet]. [cited 2021 Dec 2]. Available from: https://www.covid19treatmentguidelines.nih.gov/
     Google Scholar
  22. Planas D, Veyer D, Baidaliuk A, Staropoli I, Guivel-Benhassine F, Rajah MM, et al. Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization. Nature. 2021.
    DOI  |   Google Scholar
  23. Lopez Bernal J, Andrews N, Gower C, Gallagher E, Simmons R, Thelwall S, et al. Effectiveness of Covid-19 vaccines against the B. New England Journal of Medicine. 2021; 1: 617.
    DOI  |   Google Scholar
  24. Moline HL, Whitaker M, Deng L, Rhodes JC, Milucky J, Pham H, et al. Effectiveness of COVID-19 vaccines in preventing hospitalization among adults aged ≥65 years — COVID-NET, 13 states, February–April 2021. MMWR Morb Mortal Wkly Rep. 2021;70(32):1088–93.
    DOI  |   Google Scholar
  25. Tenforde MW, Self WH, Naioti EA, Ginde AA, Douin DJ, Olson SM, Talbot HK, Casey JD, Mohr NM, Zepeski A, Gaglani M. Sustained effectiveness of Pfizer-BioNTech and Moderna vaccines against COVID-19 associated hospitalizations among adults—United States, March–July 2021. Morbidity and Mortality Weekly Report. 2021; 70(34): 1156.
    DOI  |   Google Scholar


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